Inventor Of ToothpasteIn 1850, at the age of 23, Dr. Sheffield invented the world's first toothpaste, a formula that was manufactured in a small laboratory at 170 Broad Street, the actual site of the Sheffield factory today. It is given to but few to attain the eminence in their vocations that Dr. Sheffield has in his profession, and his practice has been one of the largest and most successful ever received by a New England dentist. For some time, in his private practice, he had been using the preparation now known to the world as Creme Dentifrice, and with such single and pleasing results that the demand prompted its making on a larger scale. This led to the erection of the laboratory on Waller Street, and, quickly following the preparation being placed on the market and its qualities becoming known, a marked increase in the demand was felt. Creme Dentifrice is unlike any other dental preparation in the market; it has been used in caring for the teeth by most critical people for years, and always with the best results. It is absolutely harmless and while not intended as a "cure-all", it has many valuable properties other than the one mentioned. This, however, is only one of the laboratory's preparations, and as an adjunct to it, the Elixir Balm is most valuable for healing, hardening and strengthening the gums as well as giving sweetness and purity to the breath. When it is used in conjunction with Creme, tartar and other affections are quickly removed or wholly prevented.